Close-up of stacked petri dishes with yellow agar medium, showing bacterial colonies growing on the surface.

Immune system effects

The gastrointestinal tract takes a prominent part in the immune defense. In fact 80% of the immune system is located in the gut.

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Immune system effects

A gastrointestinal flora in balance can enhance the immune health and contributes to and promotes a better general health.

Two trials with L. reuteri Protectis (BioGaia) have shown positive effects on prevention of infectious disease: Supplementation with BioGaia has a significantly positive effect on the incidence of common infections in children in day care and improve work-place healthiness by reducing short term sick-leave caused by respiratory or gastrointestinal infections.

BioGaia Protectis enhancing immune health

  • Interacts with the immune system of the GI tract
  • Modulates immune responses through cytokines and chemokines in tissues distal from the gut
  • Boosting immune responsiveness
  • Maintaining everyday health in children and adults
  • May reduce risk of respiratory allergy and asthma later in life

A gastrointestinal flora in balance contributes to and promotes a better general health.

BioGaia Probiotic Drops and Tablets

Limosilactobacillus reuteri Protectis has been shown to maintain digestive health and function and to keep the body’s natural defence.

BioGaia Dosage recommendations

1 chewable tablet or 5 drops daily

Comparison of two probiotic agents

Effect of a probiotic infant formula on infections in child care centres.

Weizman Z, Asli G, Alsheikh A. (2005) Pediatrics 115:5-9.
Health protection with BioGaia Protectis in children.

Results

L. reuteri significantly reduced

  • days with fever
  • episodes and days with diarrhoea
  • need to consult a doctor and need of antibiotics
  • absence from day care

Conclusions

  • Occurrence of number of febrile episodes and episodes of gastrointestinal infections were statistically less frequent in the probiotic group
  • L. reuteri (BioGaia) had a significantly superior effect compared to B. lactis
  • Significantly fewer doctor visits, fewer use of antibiotics and fewer absent days from day care

Facts

  • Prospective, randomized, placebo controlled study
  • 201 healthy children, aged 4–10 months, were studied for 12 weeks in three different groups:
  • They were given formula with L. reuteri ATCC 55730 (BioGaia) or Bifidobacterium lactis Bb-12, or formula without probiotics (control)

Randomised, double blind placebo-controlled study

Increasing workplace healthiness with the probiotic Limosilactobacillus reuteri.

Tubelius et al., Environ Health 4:25 (2005). Health protection by BioGaia in adults.

Results

  • Reduced sick days at home with short term
  • gastro-intestinal or respiratory illness
  • The frequency of sick days of ordinary workdays was 0.9% in the placebo group vs. 0.4% in the L. reuteri group (p<0.01)
  • L. reuteri: <1 sick day /individual and year
  • Placebo: 3 sick days /individual and year

Conclusions

  • Daily supplementation with the probiotic Limosilactobacillus reuteri ATCC 55730 (BioGaia) could reduce the incidence of common infections and thereby reduce short-term sick leave at a major Swedish workplace.
  • Effect pronounced in shift workers

Facts

  • Randomised, double blind, placebo-controlled study
  • 181 healthy company employees , received once daily over 3 months to use a probiotic drinking straw containing 10^8 CFU of L. reuteri (Bio- Gaia) or an identical placebo drinking straw, together with at least 100 ml liquid and completed a diary on symptoms of gastrointestinal infection or upper respiratory tract infection (common cold), duration of symptoms and number of days away from work due to such symptoms.
  • L. reuteri (n=94) or placebo (n=87).